刘胜（Liu, Sheng）

刘胜博士，中山大学中山眼科中心研究员、博士生导师，入选广东省创新科研团队。刘胜博士在中国科学院生物物理研究所获得神经科学博士学位；2006-2012在美国圣路易斯华盛顿大学医学院做博士后，研究视觉和运动感知信息处理的神经基础；2012-2016在美国贝勒医学院任助理教授，研究感知决策的神经机制；2016年9月至今在中山大学中山眼科中心任研究员。曾主持美国国立卫生研究院的科研项目，目前主持国自然重点国际合作和国自然面上项目。

回国以后，发展和改进了膜片钳单细胞测序技术，从而在非人灵长类大脑上实现了对同一细胞的神经编码信息、遗传表达信息和形态信息的全面解析，实现了高通量单细胞测序和高解析度的膜片钳单细胞测序相结合的技术，可对神经细胞类型的进完整和精确鉴别；运用膜片钳单细胞测序技术，首次解析了哺乳类视网膜节细胞的电生理、形态和基因表达多模态图谱；

研究方向：1.视网膜电生理

          2.视觉神经科学

          3.解析脑神经元类型图谱和连接图谱

代表论著：

Hao ZZ^#, Wei JR^#, Xiao D^#, Liu R, Xu N, Tang L, Huang M, Shen Y, Xing C, Huang W, Liu X, Xiang M*, Liu Y*, Miao Z*, Liu S*. Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations. Nat Neurosci. 2022 Jun;25(6):805-817. (#Co-1st author)

Huang W^#, Xu Q^#, Liu F^#, Su J, Xiao D, Tang L, Hao ZZ, Liu R, Xiang K, Bi Y, Miao Z, Liu X*, Liu Y*, Liu S*. Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse. Invest Ophthalmol Vis Sci. 2022 May 2;63(5):13.

Xiao D, Jin K, Qiu S, Lei Q, Huang W, Chen H, Su J, Xu Q, Xu Z, Gou B, Tie X, Liu F, Liu S*, Liu Y*, Xiang M*. In vivo Regeneration of Ganglion Cells for Vision Restoration in Mammalian Retinas. Front Cell Dev Biol. 2021 Oct 4;9:755544.

Tie X, Li S, Feng Y, Lai B, Liu S*, Jiang B*. Distinct Roles of NMDAR and mGluR5 in Light Exposure Reversal of Feedforward Synaptic Strength in V1 of Juvenile Mice after Binocular Vision Deprivation. Neuroscience. 2018 Aug 1;384:131-138.

Laurens J^#, Liu S^#, Yu XJ^#, Chan R, Dickman D, DeAngelis GC, Angelaki DE. Transformation of spatiotemporal dynamics in the macaque vestibular system from otolith afferents to cortex. Elife. 2017 Jan 11;6:e20787. (#Co-1st author)

Pitkow X, Liu S, Angelaki DE, DeAngelis GC, Pouget A. How Can Single Sensory Neurons Predict Behavior? Neuron. 2015 Jul 15;87(2):411-23.

Fan RH, Liu S, DeAngelis GC, Angelaki DE. Heading Tuning in Macaque Area V6. J Neurosci. 2015 Dec 16;35(50):16303-14.

Liu S, Dickman JD, Newlands SD, DeAngelis GC, Angelaki DE. Reduced choice-related activity and correlated noise accompany perceptual deficits following unilateral vestibular lesion. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17999-8004.

Liu S, Gu Y, DeAngelis GC, & Angelaki DE (2013) Choice-related activity and correlated noise in subcortical vestibular neurons. Nature neuroscience 16(1):89-97.

Gu Y, Liu S, Fetsch CR, Yang Y, Fok S, Sunkara A, DeAngelis GC, Angelaki DE. Perceptual learning reduces interneuronal correlations in macaque visual cortex. Neuron. 2011 Aug 25;71(4):750-61.

Liu S, Dickman JD, Angelaki DE. Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex. Cereb Cortex. 2011 Mar;21(3):563-73.

Yang Y^#, Liu S^#, Chowdhury SA, DeAngelis GC, Angelaki DE. Binocular disparity tuning and visual-vestibular congruency of multisensory neurons in macaque parietal cortex. J Neurosci. 2011 Dec 7;31(49):17905-16.

Liu S, Yakusheva T, Deangelis GC, Angelaki DE. Direction discrimination thresholds of vestibular and cerebellar nuclei neurons. J Neurosci. 2010 Jan 13;30(2):439-48. 7.

Liu S, Angelaki DE. Vestibular signals in macaque extrastriate visual cortex are functionally appropriate for heading perception. J Neurosci. 2009 Jul 15;29(28):8936-45.

Liu S, Liu YJ, Li B. Spatiotemporal structure of complex cell receptive fields and influence of GABAergic inhibition. Neuroreport. 2007 Oct 8;18(15):1577-81.